Transforming Growth Factor β Receptors and p27kip in Thyroid Carcinoma
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چکیده
منابع مشابه
Transforming growth factor-β
Dna2 was first characterized in yeast as an essential gene encoding a protein with both helicase and endonuclease activities involved in maturation of Okazaki fragments during DNA replication. Dna2 also plays a role in double-strand break (DSB) repair by homolo-gous recombination. The respective contributions of its replication and/or repair functions toward cell viability and resistance to gen...
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Objective: Helicobacter pylori has a well-established role in the development of gastric cancer. In vitro studies reveal increased proliferation of the gastric mucosa in the presence of H. pylori infection. It has been also shown that production of some cytokines, such as interleukin-1 beta (IL-1b) is in...
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Background: Papillary thyroid carcinoma (PTC), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. The objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in PTC with regard to age, gender, tumor size and lymph node involvement. Methods: Immunohistochemical stains were performed on 92 tissue bl...
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Transforming growth factors-beta (TGFs-/?) are representative of a superfamily whose members were first identified as regulators of morphogenesis and differentiation, and subsequently found to be structurally related. Other members of the family include the activins and inhibins, BMPs, MIS, the DPP-C gene product and Vg-1. When assayed by affinity-labelling techniques, TGFs-/? bind to three dis...
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the widespread use of sulfur mustard (sm) as a chemical warfare agent in the past century has proved its long-lasting toxic effects. despite a lot of research over the past decades on iranian veterans, there are still major gaps in the sm literature. transforming growth factor (tgf-β), a cytokine that affects many different cell processes, has an important role in the lungs of pati...
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ژورنال
عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery
سال: 1999
ISSN: 0886-4470
DOI: 10.1001/archotol.125.1.76